The Berry Bees are agents with the BIA.
That acronym stands for the Berry Intelligence Agency, an apparently independent intelligence operation. It is run by a woman named Mrs. Berry. The Bees in question are three ten-year old girls who have become operatives with this group, as indicated by an explanation from Mrs. Berry:
"Meet Juliette, Lola, and Bobby. Three ordinary girls but with the most extraordinary talents. Juliette: talented actress and mentalist. Lola: mind-blowing contortionist and amazing acrobat. Bobby: computer whiz kid and expert junior hacker. I equip them with super-cool 'berry' gadgets. As members of the DIA spy agency, they became the youngest, most talented spies the world had ever seen because there are many missions that only kid spies can solve. My name is Mrs. Berry. These are the Berry Bees. Honeycomb what may, they always save the day. They are the Berry Bees."
Bobby, codename Raspberry, has shoulder-length red hair and green eyes. She has a little brother named Fed. Her talents include computer skills, technology proficiency, and inventing. She is partial to using the Berry Brain which is a gas/goo gun.
Lola, codename Strawberry, has very long black hair usually tied up in a huge bun and dark violet eyes. She says her parents are constantly travelling the world but because she is afraid of flying, she is not with them but instead lives with Bobby's family. Oddly for someone who doesn't fly, she is awesome with acrobatics.
Juliette, codename Blueberry, has blonde hair which comes well below her shoulders and brown eyes. She is said to be a living lie-detector, able to key in on non-verbal tells of people she meets. She is said to play 19 different musical instruments. She is a natural actor and impersonator. She is very fond of throwing weapons of various types.
The Bees have three main opponents: Tara Bytes who is a criminal mastermind, Mirage who is a thief with a very handy ability, and the pair of Cosmo and Fauna Greenthumb.