Shia Shaham is an agent with Mossad.
Ramzy Yusuf Awwad is a PLO intelligence officer.
I mention the second person here even though the series is about the first because while we will follow the first through what amounts to two phases of his life with the Israeli intelligence agency, his strange relationship with the second is key to everything that happens.
The first phase, depicted in the first recorded adventure, takes place in 1982 when terrorist leader Abu Nidal was the number one target for Mossad. Shaham is given the task of finding and eliminating him. Another larger team had been on that assignment for some time and Shaham's task would not stop that one but the Mossad director had another avenue to try and he chose Shaham to be the one to take that road. It would involve making use of Ramzy Awwad.
The second phase takes place during the next two adventures and occurs three decades later. Shaham is still an operative but now one of the most senior in the department. Shaham's health is a constant worry for himself and for his much younger wife both because of the gun shot wound he had suffered a year before and because of his not unnoticeable girth that over the years had accumulated. Meanwhile his old friend and often enemy Ramzy Awwad had moved from being in the PLO and therefore a natural opponent to Shaham to being an accomplished author with several best-selling books about the Palestinian life.
In that first phase, Shaham and Awwad are both very reluctant to work with each other because there is absolutely no trust nor friendship between them and each would not have missed the other should one have died. In the second phase, both are reluctant to work with each other because neither wants to see the other in danger.