Golgo 13: Top Secret Episode

Released 1988

Golgo 13's mission is to kill the leader of the Drek group. According to Wikipedia: "The story begins when a helicopter transporting a vial of a deadly bacillus known as "Cassandra G" is destroyed near the Statue of Liberty, but the vial is nowhere to be found in the wreckage. Golgo 13 is blamed for the destruction and possible theft as a bullet of an M-16 was discovered in the wreckage, which he is known for being partial to. However, those in FIXER refuse to place blame on Golgo 13, and task him with hunting down the real assassin. On the way, Golgo 13 must pass through several areas, including East Berlin, Athens, Rio de Janeiro, and Alexander Island, which is located off the coast of Antarctica."