The Siege of S.H.A.D.E. City
Jess Lemire (writer), Alberto Ponticelli (pencils and inks), Jose Villarrubia (colors), Travis Lanham (letters)
Published in Frankenstein: Agent of S.H.A.D.E. #6 - #7, April 2012 - May 2012.
While Frankenstein and the Creature Commandos head to Vietnam to combat a super humanoid that Frank had fought alongside back in the 60's, the humanids working in the Ant Farm stake a rebellion. Told in two parts:
Part 1: The Killing of Col. Quantum!
Part 2: The Rise of the Humanids
Repackaged as part of the graphic novel Frankenstein Agent of S.H.A.D.E. Vol. 1 - War of the Monsters.